Human Growth Hormone (HGH), also known as somatotropin, is a peptide hormone responsible for stimulating growth, cell reproduction, and regeneration in humans and other animals. It is produced by the pituitary gland, a small gland located at the base of the brain.
Here are some key points about Human Growth Hormone:
Function: The primary function of HGH is to promote growth during childhood and adolescence. It stimulates the growth of bones and cartilage and helps regulate protein synthesis, leading to increased muscle mass.
Regulation: HGH secretion is controlled by the hypothalamus, which releases growth hormone-releasing hormone (GHRH) and growth hormone-inhibiting hormone (GHIH or somatostatin). These hormones signal the pituitary gland to produce or reduce HGH release, respectively.
Release: HGH secretion follows a pulsatile pattern, with higher levels typically produced during sleep, particularly in the early hours of the night.
HGH as a Performance-Enhancing Drug: Due to its anabolic effects on muscle growth and potential performance enhancement, HGH has been misused by some athletes as a performance-enhancing drug. The World Anti-Doping Agency (WADA) and various sports organizations have banned the use of HGH in competitive sports.